HORDB

ID: hor001174
Uniprot ID: A8XJC3
Protein name: FLP-18
Gene name: flp-18
Organism: Caenorhabditis briggsae
Family: FMRFamide related peptide family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Caenorhabditis (genus), Peloderinae (subfamily), Rhabditidae (family), Rhabditoidea (superfamily), Rhabditomorpha (infraorder), Rhabditina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0006937 regulation of muscle contraction; GO:0007218 neuropeptide signaling pathway; GO:0030431 sleep
GO CC: GO:0005576 extracellular region

Sequence: AYFDEKKSVPGVLRF
Length: 15
Propeptide: MQRWSGVIFITLCCLLREASAYTEPIYEIVEDDIPAEDIEVTRGNEKQDGRVFNKRDFDGAMPGVLRFGKRGGVWEKRESSVQKKEMPGVLRFGKRAYFDEKKSVPGVLRFGKRSYFDEKKSVPGVLRFGKRDVPMDKREIPGVLRFGKRDYTEEMFDKRSEVPGVLRFGKRDVPGVLRFGKRSDLEEHYAGVLLKKSVPGVLRFGRK
Signal peptide: MQRWSGVIFITLCCLLREASA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor001174_AF2.pdb

hor001174_ESM.pdb

Mass:	200592	Formula:	C83H126N20O22
Absent amino acids:	CHIMNQTW	Common amino acids:	FKV
pI:	9.26	Basic residues:	3
Polar residues:	3	Hydrophobic residues:	6
Hydrophobicity:	-25.33	Boman Index:	-2338
Half-Life:	4.4 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	71.33
Instability Index:	4324	Extinction Coefficient cystines:	1490
Absorbance 280nm:	106.43

PubMed ID: 18760316
Title: Comparative Peptidomics of Caenorhabditis Elegans Versus C. Briggsae by LC-MALDI-TOF MS